Translational Regulation of caudal mRNA by Bicoid

The work of my PhD was on the evolution of translational regulation of caudal mRNA by Bicoid in Drosophila melanogaster and other insects. Quite a lot had been done already about this: Bicoid, a.k.a “the morphogen”, was found to be both a DNA-binding and RNA-binding protein. Besides its function as a transcription factor, it was also found to be the essential player in repressing the translation of the posterior patterning factor caudal. “Bicoid recognition elements (BRE)” to which Bicoid directly binds had been identified within the caudal 3’UTR.

My PhD work was done in the Averof lab, which has moved from Crete, Greece to Lyon, France.

Advertisements

Leave a Reply

Fill in your details below or click an icon to log in:

WordPress.com Logo

You are commenting using your WordPress.com account. Log Out / Change )

Twitter picture

You are commenting using your Twitter account. Log Out / Change )

Facebook photo

You are commenting using your Facebook account. Log Out / Change )

Google+ photo

You are commenting using your Google+ account. Log Out / Change )

Connecting to %s

%d bloggers like this: